Second Journal Club

VDSers, here is the link to the next journal which covers homology models:

Kenyon, V.; Chorny, I.; Carvajal, W.; Holman, T.; Jacobson, M., Novel human lipoxygenase inhibitors discovered using virtual screening with homology models. J Med Chem 2006, 49 (4), 1356-63.

https://docs.google.com/fileview?id=0B_Gl3lMyhDsoZmM2YTRjNGUtZDI3MC00NWRiLWE3MjItMTkxMWI1MWY3ZWFh&hl=en&authkey=CNz2m_sF

Study questions to follow:

Ligand Efficiency Article

http://fbdd-lit.blogspot.com/2009/01/ligand-efficiency-or-why-size-doesnt.html

I found something that helped me figure out what ligand efficiency means.

Da’Marcus